Chapter 491

Normal human blood oxygen levels must exceed 95% to adequately maintain normal bodily functions.

However, this takes into account the oxygen consumption needs of all organs throughout the entire body.

The bilateral lower limbs are far less delicate than organs like brain tissue, the heart, and the spleen; one could say the four limbs are the most durable.

Brain tissue deprived of oxygen for five minutes will result in brain death.

Myocardial ischemia for fifteen minutes can be fatal...

According to current concepts, complete ischemia of the bilateral lower limbs for up to six hours is still a relatively good indication for limb replantation surgery.

This is still complete ischemia.

Locally, the microcirculation instrument can achieve 80% blood oxygen levels, which is sufficient to support the structural oxygen consumption needs of the lower limbs.

As for energy deficits and such, there is absolutely no need to worry; the microcirculation instrument can complete oxygenated arterial-venous blood circulation exchange, allowing easy replenishment of various electrolytes and nutrients.

Furthermore, metabolic waste is excreted through the filtration device.

With 80% blood oxygen levels and adequate nutrition, maintaining the vital lifeline of the bilateral lower limbs for several hundred hours is absolutely no problem.

Nie Mingxian held the hands of Fang Ziye and Wu Xuanqi for a full half minute before letting go, and then the three of them laughed like children.

While looking at the test rabbit's resentful gaze on one side, and the various data transmitted from the microcirculation instrument on the other.

"Lower limb, blood pressure, blood oxygen, heart pump rhythm..."

"Draw some arterial and venous blood separately, examine the metabolic structure inside each." Fang Ziye calmed down and began searching left and right for syringes.

There definitely aren't any professional venous blood collection devices here, because there hasn't been a need for such high-end configuration yet.

The microcirculation instrument is equipped with a one-way valve blood collection channel, precisely to facilitate arterial and venous blood sampling analysis at any time.

Wu Xuanqi handed a syringe with a needle to each of Fang Ziye and Nie Mingxian, saying: "You two do it; this device was created by you two."

Wu Xuanqi counts as a witness at most.

Before Wu Xuanqi arrived, Nie Mingxian and Fang Ziye had already pushed this modified micro-device to its final stages, so Wu Xuanqi also didn't dare to be thick-skinned and claim he was a participant.

At this moment, Nie Mingxian and Fang Ziye couldn't be bothered to consider Wu Xuanqi's feelings, especially Nie Mingxian.

Heard that when they used to share a rental, this guy Wu Xuanqi debauched himself in the room right in front of Nie Mingxian.

After blood collection, the samples still need to be sent to the laboratory's "inspection room" for blood gas analysis, mainly analyzing electrolyte, lactate, ketone body, and other content levels.

At this time, what needs attention is the issue of local tissue energy metabolism.

After sending off the two blood samples, Fang Ziye said: "Brother Xian, so what you proposed earlier — high-dose thrombolysis at the single lower limb distal end after amputation — the principle is feasible."

Why amputate? Generally, it's because of severe proximal bleeding and severe embolism of the distal artery, leading to poor blood supply.

Continued retention of the lower limb would worsen blood loss, and the constantly refluxing venous blood would bring metabolic waste.

Amputation is a relatively good hemostasis method, and it separates the soon-to-necrose lower limb stump from the patient's circulatory tissue.

"PCI works for coronary artery embolism in the heart; local high-dose thrombolytic drugs cannot possibly be ineffective."

"And since it's a local area post-amputation anyway, the error tolerance is even higher."

"We tried many times, and finally found that normal thrombolytic drug doses multiplied several times or even up to twenty times, once detached from the flesh body, are all safe."

"And these drugs can automatically 'metabolize' completely within a few hours." Nie Mingxian said.

After saying this, Nie Mingxian plopped down onto the chair again, leaning against the backrest, and exclaimed: "This counts as me finally getting it done before leaving Han City."

"Not overdue, and certainly not pulling up my pants and leaving."

Fang Ziye arrived last, so Wu Xuanqi and Nie Mingxian had probably seen enough, but Fang Ziye hadn't seen his fill yet, still watching carefully without stopping.

And he started taking photos from every angle.

This moment is inevitably of historical significance, worthy of commemoration by all means.

This device, though compact and modified, is undoubtedly Fang Ziye's greatest invention to date, bar none.

The development of mangled extremity and functional reconstruction surgical techniques both pale in comparison to its significance.

Fang Ziye is very clear that it's not because its technology is so original; the modification and reasoning of principles are certainly difficult, but they definitely don't compare to the development of the two techniques.

But the reason its significance is greater than the two techniques is because of its convenience.

Convenience is something any era and society must weigh.

Humans went from walking to domesticating horses and donkeys, breaking through the limits of individual speed, borrowing the power of horses and donkeys as tools so their speed was no longer limited to human instinct.

Then came the making of horse-drawn and donkey-drawn carts; human capacity to carry goods was no longer limited to individual flesh-body strength bearing weight forward.

Is riding horses and donkeys hard? Hard but not hard; definitely simpler than taming wild horses and wild donkeys; ordinary people can also learn to ride — this is breaking the threshold.

Analogous to the two techniques of mangled extremity and functional reconstruction, they are actually relatively high-threshold things; to master these two techniques, according to current statistical data from the animal laboratory —

Only professional personnel who have mastered Level 4 Debridement Technique can possibly explore the threshold; otherwise, it's all wasted effort.

And the reason Fang Ziye is so certain is because his current fellow trainee Jie Han, after failing multiple times, has cycled back into learning and practicing basic debridement technique.

Jie Han's aptitude isn't poor, at least comparable to Wang Yuanqi; Jie Han's prolonged inability to get started definitely isn't due to poor aptitude, but insufficient foundation.

Foundation is a very important thing...

Once such a microcirculation instrument comes into the world, once it is successfully mass-produced, could it be that only Fang Ziye can perform limb replantation?

It is not!

Limb replantation is actually an extension of limb reattachment; the only difference is the time window is far wider than limb reattachment surgery.

Many patients can be amputated at a lower-level hospital, then transferred to a superior hospital for limb reattachment surgery!

And other hospitals, even most prefecture-level city hospitals, can perform such limb reattachment surgery.

What they lack isn't technique, only the technique to preserve the limb intact —

After a lower-level hospital amputates, they don't dare perform limb reattachment on the stump either; if it doesn't survive, isn't that just asking for trouble.

But the appearance of this microcirculation instrument now breaks exactly this concern!

Instruments and tools can drive technological progress in most hospitals; this is where its significance lies, and the awesome part of developing tools.

Fundamentally solving a certain problem, giving people a sense of security and confidence.

Wu Xuanqi walked up to Nie Mingxian and asked softly, "You really have to leave Han City? Can't you just not go?"

"Or is it because you're unhappy?"

Wu Xuanqi roughly knew some things about Nie Mingxian and Liu Guo, but didn't expose them.

The bond between brothers and friends — absolutely don't meddle blindly.

You say a few words to him, it's just a matter of minutes, but what's affected is someone else's lifetime.

Whether shoes fit or not, only your own feet know best.

Nie Mingxian shook his head lightly: "What could I possibly be unhappy about?"

"Leaving is definitely happening — I'm still a student after all." Nie Mingxian said.

On this point, Wu Xuanqi couldn't deny it either.

Nie Mingxian is currently a doctoral student — he definitely has to go get his diploma and degree certificate in hand.

Otherwise, all those trips Nie Mingxian made would be purely for thrills.

Wu Xuanqi considered for a while before saying cautiously: "Want me to find you one in the premium group?"

"Guaranteed to be both virtuous and talented, perfect in both talent and looks."

Hearing this, Fang Ziye, who was taking photos, twitched his perked ears slightly: "Qi Ge, what group are you talking about? Can I join one?"

The so-called group — Fang Ziye had always been very curious about it.

Just never had the chance to get in.

Of course, this group was also something Wu Xuanqi told him about.

Turns out there's actually this kind of rather high-end so-called "blind date group."

Wu Xuanqi took one look at Fang Ziye and decisively shook his head: "You can't join — if you got in, I'm afraid you'd directly flip the group chat."

If Fang Ziye had no connection to Luo Tingzhu whatsoever, if Fang Ziye's current connections were even slightly narrower, Wu Xuanqi might have pulled Fang Ziye in.

But because of Luo Tingzhu, Wu Xuanqi was truly afraid Fang Ziye would directly blow up this kind of group.

You have to know, Fang Ziye right now in the department might exchange a few words with someone whose name and gender are both coded, and vent grievances in a wronged way.

Guaranteed it wouldn't take long before this group might vanish without a trace!

Fang Ziye heard this and said with an even more determined attitude: "Qi Ge, what if I say I insist on joining?"

This bastard Lan Tianluo directly took down even the Respiratory Medicine professor — Fang Ziye was also very curious about this group's operating mode.

Just why does Lan Tianluo have such huge resentment?

Of course, if necessary, Lan Tianluo venting anger is his business — Fang Ziye doesn't mind kicking him while he's down either.

Fang Ziye's formal and cold tone made even Nie Mingxian unconsciously sit up straight.

Staring blankly at Fang Ziye, he came out with: "The dragon-slaying youth — is he growing into an evil dragon?"

Normally, Fang Ziye is a pretty easygoing guy, smiling and cheerful, also polite and courteous, never losing his temper.

But today, Fang Ziye's tone is completely unlike the usual Fang Ziye.

Wu Xuanqi said with almost no hesitation: "Then I'll recommend you in — I'll tell the group owner about your identity first, you'll definitely be able to get in."

Wu Xuanqi didn't argue with Fang Ziye at all — directly agreed to Fang Ziye's request.

After asking the group owner's opinion, Wu Xuanqi even deliberately showed Fang Ziye a glance at past group announcements.

The first sentence states: This group aims to provide quality blind date candidates and basic information; all forms of coercion are prohibited.

Second, this group...

"Qi Ge, looking at this has no substantive meaning — I just want to join and lurk for a while." Fang Ziye doesn't read this stuff.

He wants to understand this group's operating mode, not the group announcements.

Also, Fang Ziye is even more curious what this group actually does.

Of course, Fang Ziye isn't afraid of Wu Xuanqi snitching to the group owner either — he's just curious, doesn't really want to know anything.

"What are you guys doing?"

"Ziye, don't you have a girlfriend? You're drilling into this group — aren't you afraid of being misunderstood?" Nie Mingxian asked curiously.

"No problem — if Tingzhu knew I was in this group, she'd be curious too." Fang Ziye said very indifferently.

"Fine, your circle is truly chaotic." Nie Mingxian still didn't know the specifics.

But he also couldn't be bothered to care.

Just, after Nie Mingxian glanced again at the rather listless Tu Tu, he said: "How about we help it reattach its leg?"

"It's been thirty-plus hours — the lower limb still has viability."

"If it's by flight, from Eastern Han to the United States is roughly enough time."

Wu Xuanqi skipped past the topic with Fang Ziye and asked: "You don't want to know the time's upper limit in one go?"

"Not that curious."

Nie Mingxian suddenly said: "Hey, you guys all know about the conflict between me and Liu Guo, right?"

Nie Mingxian's tone was casual, as if chatting about whether you two drink water or not.

Wu Xuanqi and Fang Ziye both nodded.

"Alright then! This is Zhongnan Hospital, is Han City, is your home turf — you've got eyes and ears everywhere."

"But you definitely can't monitor me and Liu Guo eating out, right?"

"Actually telling you guys — who's turning who is still hard to say!" Nie Mingxian bit down on his root/fundamental.

Clearly very displeased with someone behind Liu Guo.

Hearing this, Wu Xuanqi only then said cautiously: "Brother Xian, if Liu Guo was really persuaded by her department head, such a woman isn't worth your investment!"

Feelings aren't a transaction — if Liu Guo believed her department head and made similar demands to Nie Mingxian, then this person can stop being a sister-in-law.

This is Nie Mingxian's most essential thinking.

I'm going to your mother's Gobi desert, I want to stay at Zhongnan Hospital, and I still want to go to Vascular Surgery, you only dated me for that, you idiot?

"You can't just look at the surface of things!"

"Who among you could have thought that Chief Director Qian Zhong, Professor Qian of General Surgery, is actually Liu Guo's biological father?"

"The reason one is surnamed Qian and the other Liu is that when Liu Guo was just born, her body was too weak, so they followed an elder's idea, saying she was given to someone else as a godfather, only then would she be easy to raise."

"So Liu Guo was given a dry father, who is also Professor Qian's good friend, and got Liu Guo's name." Nie Mingxian said blandly.

"What I'm hesitating about now is whether I should 'sell myself'."

Nie Mingxian said blandly.

As soon as Nie Mingxian's words came out, Wu Xuanqi and Fang Ziye were both full of surprise.

After a few seconds, Wu Xuanqi then exclaimed: "Oh, so this Liu Guo is actually a Zhongnan super second generation?"

"Mhm, I personally feel that her father saying this to her doesn't count as anything excessive, right?" Nie Mingxian laughed until his mouth split open.

Indeed, if you swapped identities, this requirement seems not excessive either.

(Chapter End)