Chapter 67

The time was already approaching half past eleven, not early anymore.

And at this hour, there wasn't much to eat near Zhongnan Hospital; one would have to go to the other end of Han Street to possibly find a late-night snack.

But since it was agreed upon, when the two left the laboratory, they didn't need to turn off the lights; there were still people working hard inside, and everyone's experimental progress had its own differences.

Fang Ziye told Luo Tingzhu about Yuan Weihong agreeing to temporarily let Luo Tingzhu come help him with experiments; although there wasn't much contribution or achievement, being able to follow along and learn was an opportunity not to be missed.

After Luo Tingzhu and Fang Ziye walked out of the laboratory, Luo Tingzhu asked: "Senior Brother Fang, you've finished WB now, do you still have experiments to do afterwards?"

Fang Ziye's currently progressed experiments included migration, invasion, CCK-8 proliferation, cycle detection, and WB's HK2 quantitative analysis; in terms of basic experiments, it was only at the HK2 molecular enzyme molecular level that things could come to a conclusion.

Naturally, this was only the most preliminary experiments; there were still many related things that could be done.

"Currently there are mainly two explorable directions: one is to see if drugs affecting HK2 can be found, acting on tumor growth and invasion; the other is to continue deeply searching for HK2's targets, which is an extension direction for subsequent research projects."

"Then there are animal experiments; we only plan to do two groups: subcutaneous tumor model and intramedullary tumor model." Fang Ziye wasn't afraid to tell Luo Tingzhu the subsequent extension directions.

Because even if Luo Tingzhu used this to apply for subsequent research projects, the preliminary experimental research for this project wasn't done by Luo Tingzhu, so Luo Tingzhu, even relying on Professor Deng, might not necessarily be able to compete with Fang Ziye and Jie Han.

Yuan Weihong's group had preliminary research foundation; the two people's foundations were not the same.

Hearing this, Luo Tingzhu asked: "Oh, so those should be the subsequent progressable experiments and projects then?"

When applying for projects, one must pay attention to extensibility; Fang Ziye had only reached the molecular level now, extensibility shouldn't be too much. Previously Yuan Weihong also considered this point, which is why he applied for this direction.

It is a massive system that can subsequently progress very deeply.

It's just that HK2's usefulness in giant cell tumor of bone has been proven; then all factors acting on HK2 can participate in the control of giant cell tumor of bone; others haven't done it, at least haven't proven it's through HK2 acting on giant cell tumor of bone; if so, everything can be done.

Although this might not necessarily solve chemotherapy drugs for giant cell tumor of bone, however, every tumor's chemotherapy drugs are explored step by step like this, through thousands of paths; it's impossible to achieve overnight.

"Should be, the car's here, Junior Sister Luo."

"You sit in the back seat, I'll sit in the passenger seat." Fang Ziye finished speaking and went to pull open the car door.

Luo Tingzhu thought for a moment, then invited: "Senior Brother Fang, you sit in the back with me, I still want to ask Senior Brother Fang some questions."

Fang Ziye did not refuse.

While in the car, Luo Tingzhu didn't find it convenient to ask, but after getting off the car and finding a barbecue stall, ordering, Luo Tingzhu asked about the feasibility of the osteosarcoma-related pathway she planned to do.

The project pathway Luo Tingzhu planned to apply for was the mRNA osteosarcoma and PKM-related pathway's action and influence.

Such experiments were actually a layer deeper than Fang Ziye's current HK2 and giant cell tumor of bone, equivalent to processing on mRNA to see its effect on PKM.

This is similar to: you process someone else's parents, observe the effect on their child; the popular understanding is like this, of course the real principle is definitely not this logic.

Fang Ziye said: "PKM is a popular pathway; you need to find a very suitable mRNA, otherwise it's hard to make people's eyes light up."

"Moreover, osteosarcoma is also currently the hottest topic in orthopedic tumors."

"Of course, it can definitely be done, as long as you can find enough literature to support it, then this pathway can also be carried on."

Currently, research progress on tumor chemotherapy has entered a super plateau period; for forty years there hasn't been another major breakthrough or achievement.

All researchers worldwide are diligently cultivating and probing; if a breakthrough is obtained, overnight wealth and overnight fame are not a worry at all.

It's just that this opportunity is very hard to encounter, equivalent to fishing for a needle in the ocean.

You do pathways, I do pathways, everyone sees whose luck is good.

Without breakthrough progress, one can only accumulate basic skills, go deep along one's own research line, peel away the mysteries of pathways and their upstream and downstream layer by layer; being able to make one's own cell lines and pathways the most comprehensive is also a kind of academic contribution.

Others will also recognize your capability and strength; it's not necessarily true that you must directly produce a very mature anti-tumor drug.

Wanting to achieve overnight is like a eunuch chatting nonsense, groundless talk.

"Junior Sister Luo, actually if you feel osteosarcoma is too popular, choosing a relatively more obscure tumor to apply for a project is also a good choice."

"No need to specially squeeze into the most popular pathways." Fang Ziye gave Luo Tingzhu a suggestion for a way out.

"That's true too. Thanks, Senior Brother; people in the lab all say you're the most warm-hearted." Luo Tingzhu smiled, neither agreeing nor refusing.

Although she's a PhD, she's this kind of PhD; because accumulated time isn't enough, although she graduated early, she also got employed early, so she still needs to further thicken her foundation.

Having enough achievements is a benchmark for demonstrating one's research capability...

Fang Ziye didn't reply, thinking: if I didn't have something to gain when doing experiments, I wouldn't be this generous either; actually helping with some experiments, I can still mooch some reagents, and get knowledge points; this kind of happiness is fundamental.

After the late-night snack, Fang Ziye sent Luo Tingzhu to the school gate and bid farewell, not going further towards the dormitory; inside the school there are security guards on watch, it's still relatively safe.

After returning home, Fang Ziye hurried to wash up and sleep; looking at the tempting, three-digit high knowledge points, Fang Ziye also didn't know for a moment where to add points.

Keep them for now, what if they're useful later? As long as there's no rush to use them, save up first, add points to a Level 4 skill, aim for the PhD graduation requirement training room standard to benchmark against.

But thinking of the pie Professor Deng drew, Fang Ziye also had a bit of a headache.

Trauma Surgery Training Room 801, the real graduation standard, is the PhD student graduation standard; after graduation, there's a very large chance of hospital retention.

In Yuan Weihong's cohort, it was graduate and stay; but now it's increasingly competitive, graduating and staying requires research to have certain capability.

Suture technique's skin jelly suturing, incision technique's pork anatomical separation, debridement technique's crushed pork plastic surgery, muscle suturing, osteotomy, closed reduction of fracture technique, bone defect splicing technique, bone plastic surgery, bone flap design...

The early graduation pie Professor Deng drew?

(Chapter End)