Chapter 806

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Protagonist:

Fang Ziye

Fang Ziye glanced at Luo Tingzhu and said, "Tingzhu, why don't you and Tian Luo go keep Dad company?"

"What I'm doing here is extremely important."

Luo Tingzhu is Fang Ziye's wife; the two of them had long agreed on many secrets unknown to outsiders.

Everything Fang Ziye is doing now is actually preliminary preparation for the 'ALS' research project; the ALS project is too difficult, even more intractable than spinal cord injury relatively speaking.

He can only accumulate step by step; he cannot achieve it in one step.

Luo Pan is his own father; Luo Tingzhu naturally nodded: "Alright then, Senior Brother, you've worked hard."

Luo Tingzhu still couldn't change her habit of address, continuing to call Fang Ziye Senior Brother.

"Where are you off to again?" Liang Xia walked out from the kitchen, carrying two fruit platters.

"I'm going to the lab... Mom... you guys rest." Fang Ziye said.

Liang Xia's eyes bulged as she said, "What's so good about that lab of yours? You just got married and you don't stay home properly."

These words were as if explicitly saying, if you don't stay home and make a person, when will my grandson come out.

Luo Tingzhu's face was red.

Fang Ziye slipped away directly, saying, "Mom, those words of yours are unacceptable. I go to the lab to contribute to the health of all humanity; you need to have a big-picture perspective."

Liang Xia naturally didn't stop Fang Ziye either; where would she dare to stop him.

Although she is a rural woman, she also knows she has no way to assist Fang Ziye's career, and dares not disturb him even more, afraid of delaying her son's future.

She has long been unable to help Fang Ziye.

"Tingzhu, let Mom tell you, Mom and your Dad are both still young, your Dad and Mom are also young; if you have a child, we can bring it up, you don't have to worry about anything..." Liang Xia could only do ideological work on Luo Tingzhu.

Although Luo Tingzhu's cheeks were somewhat red, she was already married, so she wasn't as shy as before; she lowered her head and said, "Mom, having a child isn't that urgent a matter..."

In the animal laboratory, Liao Jia and Nie Mingxian, the first time they saw Fang Ziye, instead of continuing yesterday's congratulations on the happy marriage, cursed roundly: "Fang Ziye, are you made of spinal cord injury cells?"

"How can you dare to guess like this?"

"Spinal cord injury, the acute phase is still not suitable for treatment; only the chronic phase can be treated."

"At least, if it's microcurrent stimulation, the acute phase is unsuitable; on the contrary, it will worsen the patient's condition."

Hearing this, Fang Ziye said disgruntledly, "What do you mean I'm made of spinal cord injury cells?"

"That is to say, after so long of experiments, you've already replicated this theory in animal models?"

"Microcurrent stimulation during the acute phase of spinal cord injury will only worsen the functional deficit of the spinal cord injury, and will not provide any benefit to the patient's functional recovery?"

Liao Jia nodded: "Yes, at least the so many batches of experiments you've done support this result."

"Spinal cord injury treatment cannot be rushed, especially the acute injury phase; the circuitry channels within the gray matter and white matter are in a disordered state. At this moment, microcurrent stimulation may cause information to scatter chaotically, damaging the nerve synapses below."

"Before a new treatment method is developed, the treatment window for spinal cord injury has already settled; it must be one week after acute injury, two weeks is even better."

"Data for over one month temporarily still has no results!"

According to traditional logic, early detection, early treatment.

Spinal cord injury just happens to go the opposite way: early detection, slightly late treatment. General research teams would probably need a very long time to discover this point, yet Fang Ziye guessed it in advance based on his own knowledge reserve.

Don't look at it as just this one sentence; this is merely the theory of treatment timing, but it could be the comprehensive result of a research team over several months or even a year!

It is also a huge advancement!

Understanding a disease type is not just about what method to use for treatment; one must also be especially clear about the indications, contraindications, and timing selection of the treatment method!

Most disease types emphasize early detection, early treatment, without exception, but now a special case has appeared.

If Fang Ziye hadn't been able to consider this clearly, and only thought to bury his head in developing the spinal cord injury treatment method.

After the treatment method matured, medical teams would definitely want to try it on emergency patients; then, lacking Fang Ziye's strong knowledge accumulation, they would persist with microcurrent.

Praying to follow the principle of early treatment, and then electrocuting the patient into an irreversible paralyzed state, and only after experiencing a very long time of trial-and-error cost would they conclude the emergency phase cannot be treated — then some patients would be unlucky.

"This sentence is very valuable!!" Fang Ziye pursed his lips, then asked Nie Mingxian: "Brother Nie, do you have any ideas on how to reconstruct blood supply within the spinal cord?"

The spinal cord also needs blood supply; without blood supply it will directly necrose.

If the structure is all thoroughly necrosed, what channels are there to speak of?

The acute phase being unsuitable for microcurrent stimulation doesn't mean nothing at all can be done in the acute phase!

Whether decompression should be done, whether blood supply reconstruction can be attempted — these are all issues that need to be explored.

Spinal cord injury has two phases: acute and chronic. Fang Ziye feels the team's capability is enough, so naturally he doesn't want to only tackle one phase.

With the current team manpower, division of labor can proceed.

"No ideas for the time being; my teacher doesn't have any better solutions either. Isn't this something we were waiting for you to finish your wedding leave to discuss together?"

"Right now, we have already figured out some routines for the treatment of chronic-phase spinal cord injury."

"But the previously guessed direction — that acute-phase treatment could achieve better efficacy — has been negated."

"Fang Ziye, so now we can open up clinical cases and promote this staged surgical technique into clinical practice."

"Around June, after the fourth batch of animal experiments ends, we can start large-scale clinical trials!"

"Good! June it is; the procedures must be completed. Even if it's a bit later, it doesn't matter." Fang Ziye nodded.

"We cannot gamble. Research can gamble on animal models, but not on patients. On patients, we can at most make discoveries."

After Fang Ziye finished speaking, he looked again at the data collected by Nie Mingxian and Liao Jia, nodding repeatedly: "So, our understanding of spinal cord injury treatment has deepened another step."

"First, patients in the chronic stable phase without complications can undergo surgical treatment directly."

"Second, for patients in the acute phase, microelectrode stimulation therapy is a relative contraindication; before a better solution is found, it is listed as an absolute contraindication."

"Third, the bridging electrode is a supplementary surgical technique to the needle electrode's continuous stimulation, suitable for spinal cord injury patients with multi-site damage or large-area damage."

Why is treatment R&D for a new disease type difficult? Because every step could be a pitfall, and the understanding of every single knowledge point requires going through a large amount of theoretical argumentation and experimental verification."

"You can't rely on guessing!"

After speaking, Nie Mingxian asked: "Are you free today? You have too many friends and brothers; yesterday there was no way to accompany you for a good drink. Are you free today?"

Liao Jia directly started scolding: "No, Nie Mingxian, you've never been married, don't you have a brain?"

"Yesterday Ziye got married, today you ask him to come over to see the surprise, acting as a gift is icing on the cake, but today you want him to accompany you drinking?"

"Ah ha?"

Nie Mingxian retorted, mocking: "Can't do it?"

"Unlike some people, who didn't even give a sip of wedding wine, doing some travel marriage, shotgun marriage."

Fang Ziye heard this and immediately realized Nie Mingxian was pointing at the mulberry to curse the locust — he was just using his own marriage as a pretext to scold Liao Jia for not acting human, getting married in such a rush.

Liao Jia pointed at Nie Mingxian, unable to squeeze out a single word.

His wedding didn't even have a formal "etiquette" of treating guests to meals; he only cared about the two of them enjoying themselves, so of course Nie Mingxian could open fire.

"You two continue arguing; it's still early, I should still make it in time for lunch."

"We're all going to my father-in-law's house for a meal." Fang Ziye said.

Liao Jia asked: "Isn't it the third day before returning to the bride's parents? How come you're going today?"

Fang Ziye said: "Hey, fixed customs are fixed, but you also have to adapt to circumstances. My father-in-law plans to make a trip to Enshi, to have Old Dean Chen Song take a look, see if Traditional Chinese Medicine methods can suppress the progression of ALS."

"Is Old Dean Chen's time that easy to book?"

"Oh oh." Liao Jia nodded.

Although Chen Song also came to the wedding scene, attending a wedding and diagnosing an illness are two different matters; Chen Song currently no longer goes out for consultations.

Even if he were to accept a consultation, it would have to be through special channels.

Chen Song's own legs and feet are inconvenient, and he might still need Chen Guangbai and others to assist him with other examinations, before he acts as the midbrain analyzer.

The current Chen Song's own hands and feet are also not too convenient, and he feels weak too.

Hearing this, Nie Mingxian asked in a low voice: "Ziye, you say, given Old Dean Chen's current condition, should it be classified as intracranial brain parenchyma damage? Does he have a chance to reference the spinal cord injury treatment plan and snatch back some function?"

Fang Ziye replied: "You should remove Old Dean Chen as the subject; if it's a patient with intracranial brain parenchyma damage, then it can be referenced a bit." "Old Dean Chen Song's current symptoms are originally just functional weakening; you still want to perform optimization treatment on him?"

"Can spinal cord injury patients reach Old Dean Chen Song's current functional level after treatment?"

"You want to use Old Dean Chen Song as a live 'cosmetic' experiment?"

"A function, from nothing to something, is called reconstruction."

"From something to good, that's called cosmetic enhancement."

"Reconstruction isn't even figured out yet, and you're already thinking of cosmetic enhancement — purely taking too big a step, easy to tear your balls."

……

"Dad, the research project I'm doing isn't as mystical as Tian Luo and Tingzhu say; compared to your previous research, it's the great wizard seeing the small wizard." After arriving at Luo Pan's temporary lodging, Fang Ziye drank tea while replying with slight humility.

Luo Pan chose to settle in Han City for two purposes.

One is that Han City is more livable than Henan Province; second, Luo Pan's father spent his remaining years here.

Although he returned to his roots after death, Luo Pan isn't that particular; he actually quite wanted to see the city where his father spent his remaining years.

Luo Pan laughed: "What great wizard small wizard with research projects? Don't look at how mystical the outside wears; in basic physics and applied physics aspects, the gap between us and foreign countries is still a bit large."

"Especially in basic physics, the foundation is very weak."

"Our country's research is only better than most countries, but not top-tier."

"So, listening to Tingzhu and Tian Luo's description, Little Fang, your research project's degree of advancement will be even closer to the scientific frontier than what we do."

"It's just that we focus more on practicality." Luo Pan dared not speak his work details, fearing they'd be passed on, so his wording was extremely cautious.

Lan Tianluo said: "Senior Brother, you don't need to be too humble; our research project group is originally quite excellent."

Lan Tianluo seemed to really want to show off in front of his own father; this is perhaps every boy's dream in youth, a 'dream' that feels ridiculous in middle age and old age!

Luo Pan asked: "Are you three all core members of the research project group?"

"Are you two sure it's not Little Fang forcibly bringing you along? Holding you up?"

Luo Tingzhu and Lan Tianluo both reddened slightly upon hearing this.

Their own father isn't as easy to mislead as Fang Ziye's parents; he knows quite a lot.

"Dad, that also requires Senior Brother to be able to carry and willing to carry; to be a screw, you first have to be iron yourself; temporarily there's still no screw made from mud." Lan Tianluo became very sensible again and said.

Luo Pan replied: "That's true; current tech level still can't use mud as a screw."

"Love the line of work you're in; that's good."

Lan Tianluo suddenly said: "Dad, you won't think I'm a deserter, right?"

Luo Pan shook his head: "Different aspirations, no distinction of high or low, noble or base."

"The times are much better now; freedom is very high; we must respect everyone's free choices."

"Before I just felt your talent was good; didn't expect your talent could be this good, just missing that final kick, almost catching up to my rear."

"The me in youth greatly worshipped your grandpa. The middle-aged me somewhat doubted my own choices; the current me only wants to watch you all become freer and freer."

Fang Ziye laughed lightly: "Dad, Enshi counts as a pretty good place; after you and Aunt Min go, you don't have to rush back; slowly recuperate."

"We'll also come over to see you often."

"Mainly because currently, modern medicine temporarily has no means to suppress disease progression; otherwise, you staying at Han City Yangyuan would be pretty good."

Luo Pan's work nature is related to military industry, so Luo Pan can also enter the Military Region Yangyuan, and is among those enjoying special priority.

Fang Ziye did not pursue asking what identity Luo Pan actually was, why at the wedding he could make that person who had pressured him so respectful, because none of this mattered anymore.

The current Luo Pan is just a patient, an older middle-aged person awaiting treatment.

Luo Tingzhu is four years younger than me, only twenty-seven this year! Even if Luo Pan married late, he isn't actually at normal retirement age yet; it's just that his body couldn't endure it, so he retired.

"Actually it's not bad, just inconvenient, no other particularly painful feeling; compared to Senior Deng, I'm much luckier." Luo Pan said.

Luo Pan's ALS hasn't reached a particularly severe deterioration phase yet.

Currently, Traditional Chinese Medicine methods also cannot guarantee slowing it down, but based on the basic logic of Traditional Chinese Medicine, as long as it's an illness, there is a way to "slow it down"!

Fang Ziye can only give it a try!

Fang Ziye smiled and said: "The purpose of the predecessors' efforts and sacrifices, isn't it to make the younger generation a little happier?"

"Just like, Dad you and my parents worked hard, just to give us a better life — same principle."

"You, you can expect even more."

Although Fang Ziye is powerless now, he is on the path; he needs time, to seize time, and he doesn't dare promise Luo Pan anything.

Aunt Min Limin came out at this moment: "Xiao Fang, eat more fruit, supplementing vitamins is good for your body."

"Of course, you guys definitely understand medicine better than me."

Fang Ziye stood up and said: "Mom, you rest a bit too; we just ate until a bit stuffed, can't eat any more right now."

Min Limin nodded upon hearing this, and after sitting down she added: "Xiao Fang, I heard you're researching spinal cord injury, right?"

"Any progress?"

"I have a friend, not old either, previously suffered trauma, now left leg completely has no strength, seems to be Brown-Séquard Syndrome, also spinal cord injury; she entrusted me to ask..."

Paralysis patients due to spinal cord injury in Eastern Han are not few; rigorously speaking, anyone could probably find several such patients through relatives.

Mainly because the population base is very large.

"Not possible yet, our Department hasn't opened clinical trials, at the latest we have to wait until June."

"Our spinal cord injury surgery patients for May are already fully booked."

"Mom, this disease type has reached a stable phase, won't deteriorate too much either; why not wait a bit more..."

Min Limin is not Luo Tingzhu and Lan Tianluo's biological mother, but she has had no children all her life, and currently counts as their mother; Fang Ziye also changed how he addresses her long ago.

Instead, Luo Tingzhu still calls her Aunt Min.

"Oh, it's fine, I'm just asking, not asking you to arrange hospitalization or anything now."

"Not an urgent matter, just wait a bit more."

"You guys are really amazing; my friend's connections aren't shallow, she's inquired at famous hospitals all over the World, also didn't find any place that could give her good news..." Min Limin gave Fang Ziye a thumbs-up.

From a certain angle, Fang Ziye indeed pioneered spinal cord injury treatment, belonging to the first person of this Research Project in the current era.

……

Next Day.

Fang Ziye and Luo Tingzhu, the two of them, saw Luo Pan and Min Limin off onto the Administrative Special Car, only then walking back slowly hand in hand.

Luo Tingzhu asked somewhat nervously: "Senior Brother, during Chief Resident period, is it very hard to endure?"

"Tian Luo only has one and a half days of Vacation, returned to the Department yesterday afternoon; just now I called him, his tone still wasn't too good."

Fang Ziye nodded: "During Chief Resident period, very busy, very tired; can't achieve such Round and Complete Emotional Management."

"His leave is hard to get; when he came out, it was all others covering his shift..."

Big Brother Qin Geluo is really Unlucky; previously he supported Fang Ziye, now he still has to support Lan Tianluo.

This Attending burden is very Heavy.

"Senior Brother, our team has already started basic principle research on Peripheral Nerve Degenerative Lesion; believe there will be certain progress before long."

"This way should be able to accumulate some Preoperative research foundation for my dad's ALS, right?"

"If spinal cord injury treatment can be more perfected, this New Disease Type ALS, also isn't impossible to Gnaw." Luo Tingzhu's tone was serious, Rigorous.

She grew up: one for herself, two for her own father, three for her own Dream.

The Stable Cell Line of Peripheral Nerve Degenerative Lesion, is what she and Lan Tianluo and them independently Developed; although Entrusted/Depend on the Yangyuan's Research Project funding, being able to produce it is awesome.

Some things, aren't achievable just by spending money... (Chapter End)