Chapter 1536: 1489 Precautions Point Eight

He glanced at Zheng Ren and Su Yun sitting nearby, and said contemptuously: "You hired two security guards, dressed in white coats pretending to be doctors—do you think that's enough to get away with it?"

"Hey, who said we're security guards?" Su Yun was eating melon seeds watching the excitement, never expecting to get dragged in, and she said unhappily.

"Zheng Lao Ban, Doctor Su..." Lin Ge didn't expect the fire to spread; at this moment he felt a bit flustered.

Just now I handled this dispute, didn't think much of it. But I never expected to drag Zheng Lao Ban into it, and now it's blown up.

"Don't make a fuss, Su Yun." Zheng Ren held Su Yun down, smiling: "You two talk; I'll wait with Su Yun."

"You're wearing white coats—come, tell me, why are pills coming out in the stool?" the middle-aged man said.

He thought Lin Ge was too slippery to handle. These two young security guards probably don't know anything either, and they just happened to be sitting here.

Young people, they're likely to say the wrong thing. Once I catch them, it'll be interesting.

"Nifedipine controlled-release tablets are indeed not fully absorbed." Zheng Ren said: "Your situation is the most common case."

"Common?" the middle-aged man scoffed, "Then why haven't I heard anyone else talk about it?"

Zheng Ren wanted to say, not many people actually look back after finishing a bowel movement.

But he couldn't say that—saying it would start a fight. Although he wasn't afraid of fighting, it wouldn't be good to hurt someone.

"Zheng Lao Ban, you..." Lin Ge saw Zheng Ren speaking, about to ask if you also understood the nifedipine controlled-release tablets, but before the words came out he felt foolish.

How could Zheng Lao Ban not understand?

You can't just see him as a junior clinical doctor; he's a visiting professor at Mayo Clinic.

"Sir, Professor Zheng from Mayo Clinic's visiting faculty is right here—let him explain it to you." Lin Ge said slowly.

"Mayo Clinic? What's that? Sounds like a small clinic. Is it in Sanlitun or Zuojiazhuang?"

The middle-aged man said disdainfully: "What can a clinic doctor do?"

"If you have time, look up Mayo Clinic online to avoid misunderstanding." Lin Ge smiled and didn't continue explaining.

Zheng Ren searched, took out a sheet from the printer, walked to the coffee table, and said gently: "Let me explain."

"Nifedipine controlled-release tablets are indicated for hypertension or chronic stable angina due to coronary heart disease." Zheng Ren's voice was weighty, giving an irresistible sense of authority.

"If you had carefully read the instructions, you would have noticed the warning: do not bite, chew, or split the tablet. After the active ingredient is absorbed, the empty shell passes intact through the intestines." Zheng Ren said.

"What?!" the middle-aged man stared for a moment.

He simply didn't believe what Zheng Ren said. Just seeing Zheng Ren's expression and calm manner made him a bit uneasy.

From his demeanor and expression, the middle-aged man could tell Zheng Ren was speaking the truth!

"Director Lin, print him a copy of the instructions." Zheng Ren said, looking at the middle-aged man.

Lin Ge stood up, went to the computer, opened the file, found the nifedipine controlled-release tablet instructions, and clicked print.

"The nifedipine controlled-release tablets sold by the hospital come in two specifications: one produced by Germany's Bayer, the other domestic." As he spoke, Zheng Ren glanced at the sealed plastic bag on the coffee table: "Judging by the structure, it must be the imported version—that's Germany's Bayer."

"If I remember correctly, the imported nifedipine controlled-release tablet's instructions have a similar statement in point eight of the precautions."

Lin Ge brought over a slightly warm A4 sheet and handed it to the middle-aged man.

"Point eight: this product has an indigestible shell, which allows the drug to be slowly released and absorbed in the body. When this process ends, the intact empty tablet can be found in the feces."

Following Zheng Ren's instructions, the middle-aged man effortlessly located point eight of the precautions.

His face turned pale in an instant.

"Impossible!" the middle-aged man whispered.

"If you think it's impossible, or if there's any problem with these documents, you can go home and check the instructions for the nifedipine controlled-release tablets you bought yourself." Zheng Ren smiled slightly, "It should be no different from the one printed by the Medical Department."

Director Lin sighed, having worked his whole life, he'd encountered dozens of such objectionable patients. Now all he could do was hold the instructions and explain them.

Precaution point eight…

I wouldn't remember it in such detail.

Zheng Lao Ban has a great memory, though—do they often use nifedipine controlled-release tablets in the Intervention Department?

"How is that possible?" the middle-aged man wondered aloud, "How could there be empty tablets?"

"Sir, the mechanism of controlled-release tablets differs from what we usually think of as medication." Zheng Ren explained gently: "Take the nifedipine controlled-release tablets you're using as an example—they're a dual-chamber osmotic pump system."

"The feature of this formulation is that during release, the dosage form's shell does not change. The driving layer absorbs water and swells, pushing the active ingredient out through tiny pores in the semipermeable membrane."

While speaking, Zheng Ren drew a three‑dimensional circular structure on the A4 sheet.

Because the height is small, it doesn't look like a cylinder no matter how you look at it.

The middle-aged man felt it looked familiar—it was just the nifedipine controlled-release tablet he takes, magnified ten‑fold or so.

"The dosage form's shell may remain intact in the body and be expelled with the stool."

"Why didn't you tell me?!" the patient said, a bit angry, feeling the hospital had deceived and played him.

"That's right—go home and look at the drug's outer packaging. If I'm not mistaken, the top front has a red background with white lettering that reads "nifedipine controlled-release tablets."" Zheng Ren said while sketching the medicine box.

The middle-aged man was speechless, not knowing what Zheng Ren was talking about.

"Below is a yellow stripe with the drug's brand name. Further down, slightly right of center, there's a box that reads: "Do not bite, chew, or split the tablet; after the active ingredient is absorbed, the empty tablet passes intact through the intestines."

"……" the man was speechless.

Zheng Ren's drawing was so lifelike that he vaguely recalled a similar image in his mind.

But does it really say that on the label?

Lin Ge then brought over another sheet, an image of the nifedipine controlled-release tablet's outer packaging.

Sure enough, just as Zheng Ren had said, the text appeared in four lines before the man.

"It's fine—just a misunderstanding." Zheng Ren chuckled and said: "This is completely normal; even medical professionals don't all know the mechanism of controlled‑release tablets."

Having said that, he pushed the A4 sheet with the drawing of the tablet structure and packaging toward the middle‑aged man.

"Yes…… sorry."

……

……

Note: Perhaps, 80% of medical staff in the local area wouldn't know this.