Chapter 2173: with translation of title line (which is line [1] but we need to translate the title

2098 Prepare for liver transplant (Zheng Lao Ban happy birthday! Extra chapter ×5)

Acetaminophen was formerly called phenacetin; as the name suggests, it can reduce fever and relieve pain.

The drug works by inhibiting prostaglandin synthase in the hypothalamus thermoregulatory center, reducing the synthesis and release of prostaglandin PGE1, leading to peripheral vasodilation and sweating to achieve antipyretic effect; its antipyretic strength is similar to that of aspirin.

Its analgesic effect is weak, effective only for mild to moderate pain.

N-acetylcysteine, a thiol donor, is the specific drug for acetaminophen poisoning.

Zheng Ren saw this item in the medical orders, knew the ICU had already administered symptomatic treatment, and so said nothing more.

The critical care capability of 912 is quite strong; aside from the strange situation of urine discoloration caused by propofol, Zheng Ren felt there was no need for him to overstep.

For a patient with acetaminophen poisoning leading to liver failure, collective effort is needed for treatment.

This is a clear-cut diagnosis; an experienced old doctor can tell what the disease is with just a glance.

But treatment is very difficult, difficult upon difficult.

"How could they have taken so many Yin Qiao tablets?" Su Yun looked at the medical record, frowned, and said, "Do they really think Yin Qiao tablets are traditional Chinese medicine?"

Zheng Ren and Professor Yang both sighed, and nobody said anything.

The instructions for Yin Qiao tablets read: "Sterile surgical gown"? Wait, that's wrong. Let's correct: The instructions for Yin Qiao tablets read: "Disperse wind and relieve exterior, clear heat and detoxify." Used for fever and headache, dry cough, sore throat due to wind-heat cold.

Standard Chinese medicinal terminology gives the impression that this is a Chinese medicine.

When having a cold, many people are willing to take a course of Yin Qiao tablets orally, and the effect is indeed good.

But if you carefully read the Yin Qiao tablet instructions, its ingredients are not that simple.

Honeysuckle, forsythia, schizonepeta, fermented soybean, light bamboo leaf, arctium fruit, reed rhizome, platycodon root, etc., licorice, chlorpheniramine maleate, acetaminophen, vitamin C, menthol oil.

Chlorpheniramine maleate, also called pheniramine, is an antihistamine drug.

This drug component exerts an anti-allergic effect by antagonizing H1 receptors; it is mainly used for rhinitis, skin mucosal allergies, and to relieve symptoms such as tearing, sneezing, and runny nose associated with colds.

Furthermore, it also contains acetaminophen, a drug component that relieves symptoms in small doses but causes liver failure in large doses.

Each Yin Qiao tablet contains more than 100 mg of acetaminophen.

So its efficacy is good, but after all the twists and turns it still comes back to acetaminophen.

Moreover, other cold medicines also contain acetaminophen; this child named Chen Li not only took double the dose orally, but also used several drugs in combination.

The intake of acetaminophen … is almost a lethal dose.

Every drug, while producing its effect and giving the body benefit, also carries hidden risks.

Excessive intake, not to mention medicine, even eating bananas won't do. Not to mention eating fragrant, even drinking too much water won't do.

The two words 'appropriate amount' are correct.

Zheng Ren looked at the medical record, his brows furrowed so tightly they seemed about to tie together, like the strap of a Sterile surgical gown.

The child named Chen Li is hard to save; Zheng Ren made a judgment in his heart.

During the process of reviewing the medical record, the heads and professors of the relevant departments in the hospital came one after another.

The hospital side had Vice President Yuan preside over the full-hospital consultation; Director Ye of the Medical Department and Deputy Director Lin all attended.

Just seeing how seriously the hospital took it, everyone's hearts sank a bit more.

Unlike diseases such as cancer, for cancer patients it's just an illness; life and death are fate, and as long as you do your best, that's enough.

But what we face now is a young college student who has studied hard for over ten years, hasn't yet entered society, and is about to lose his life out of the blue.

Just this point alone, Zheng Ren feels the patient's family cannot bear it.

When the white-haired send off the black-haired, this is the greatest sorrow in the world; in the mortal realm, nothing is more tragic.

The ICU case history was reported by the Inpatient Chief, who tried to be concise in reporting the known history; the doctors who arrived later thus had a basic understanding.

For acetaminophen poisoning, acute liver failure, abdominal effusion, coagulopathy, and more than ten other diagnoses are clear and explicit.

Meanwhile, the ICU has already begun platelet transfusion and is using artificial liver blood purification technology to treat the patient.

Artificial liver blood purification technology refers to plasma exchange and blood adsorption technology.

It adsorbs inflammatory substances or toxins dissolved in the blood onto solid materials with a large surface area, thereby removing inflammatory substances and toxins from the blood.

For the student named Chen Li, it suffices to filter out the acetaminophen remaining in his liver and blood.

Artificial liver technology is specifically used for blood detoxification.

It adopts a 'blood exchange' method to remove toxins from the patient's plasma, i. e., replace the toxin-containing plasma with healthy plasma, each time exchanging about 50% of the total plasma.

But this is a measure of locking the stable door after the horse has bolted; it prevents residual acetaminophen in the plasma from continuing to damage the liver.

However, for an already damaged liver, artificial liver blood purification technology cannot treat it.

In 1986, Professor Li Lanjuan and her team at the First Affiliated Hospital of Zhejiang University began researching and clinically applying this technology.

By now, it has become a fairly mature technology; the critical care doctors of 912 have mastered it skillfully, and its application poses no problem.

After the case history was reported, next came the statements of various department heads and professors.

Actually, there isn't much that can or needs to be said.

The disease is just this disease.

The situation is just this situation.

The patient's onset was rapid; although admission was timely and response appropriate, the condition is not optimistic.

This point can be clearly seen on the faces of the ICU Inpatient Chief, the associate professors, and the department heads.

They have a judgment on the patient's condition, hoping that after symptomatic treatment the patient will recover quickly.

However, from taking over to treatment, they have their own judgments.

Rich clinical experience silently says that although all treatment measures have been employed, the probability of the patient's recovery is not high.

Not to mention the expensive treatment costs, the patient's daily expenses are at least over 50,000. Speaking only of the severity of the condition…

Thinking of this, Zheng Ren feels a bit of a headache.

"I suggest preparing both ways, doing organ transplant matching; if conservative treatment fails, we can perform a Liver Transplant Surgery." Professor Yang spoke, and he said it very simply.

"Where is Doctor Zheng?" Vice President Yuan looked at Zheng Ren and asked solemnly.

"I agree with Professor Yang's opinion; I haven't seen the patient yet, but according to the medication dosage in the medical record, the patient has ingested too much acetaminophen. I think the possibility of improving or correcting liver failure through various emergency measures is not great."

"I suggest preparing for a liver transplant surgery... if we can find a liver source."

Zheng Ren said firmly.

Liver transplant, in Zheng Ren's view, only a liver transplant can save this child.